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Survival benefit of cetuximab for metastatic colorectal cancer

in the Journal of Clinical Oncology shows KRAS is the only validated biomarker which is predictive for the efficacy of... evaluation of overall survival (OS) according to KRAS mutation status in patients with metastatic colorectal cancer (mCRC), and...

Studies unpick why bowel cancers become resistant to treatment

by developing changes in a gene called KRAS, according to new... with normal versions of a second gene called KRAS, so a genetic test is used to identify these people before starting... cancer, resistance, EGFR, KRAS, cetuximab,...

TCGA study shows colon and rectal tumours constitute a single type of cancer

ARID1A, FAM123B/WTX, TP53, SMAD4, PIK3CA and KRAS), the scientists identified other genes (ARID1A, SOX9 and FAM123B/WTX) as...

Breast cancer gene provides vital clue to bowel cancer drug resistance

offered anti-EGFR drugs, patients are given a KRAS test. Around 30-40 per cent of tumours carry a faulty KRAS gene, which makes...

Healthy lifestyle choices add up to cut bowel cancer risk

for those who adopted all five. Lead author Krasimira Aleksandrova said the findings show that more than one in five of male...