Statins linked to lower risk of early death in patients with colorectal cancer
09. 05. 2019 | Wiley Press ReleaseUse of statins before or after a diagnosis of colorectal cancer was linked with a lower risk of premature death, both from cancer and from other causes, in a Cancer Medicine analysis of published studies [1].
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The meta-analysis included 14 studies involving 130,994 patients with colorectal cancer. Pre-diagnosis statin use was linked with a 15 percent lower risk of dying early from any cause and an 18 percent lower risk of dying from cancer. Post-diagnosis statin use was linked with a 14 percent lower risk of all-cause death and a 21 percent lower risk of cancer-specific death.
“Considering that statins are low-costed and wildly-used agents worldwide, we believe our updated meta-analysis can provide new insights into optimising adjuvant treatment of colorectal cancer,” the authors wrote.
Reference
- Li Y, He X, Ding Y, Chen H, Sun L. Statin uses and mortality in colorectal cancer patients: An updated systematic review and meta-analysis. Journal Cancer Medicine 2019; 8(6):3305–3313. doi: 10.1002/cam4.2151.
klíčová slova: statins, colorectal cancer, early death, meta-analysis
